News

Congratulations to Youmna Atieh, Baptiste Libé-Philippot, Léo Guignard, Emmanuelle Leblanc and Séverine Platel.

Discover how members of our community are making an impact outside the walls of the institute through public outreach and creative initiatives.

An asymmetric molecular program hides behind the production of bilaterally symmetric axons.

We would like to extend a warm welcome to Julia Schaeffer, Baptiste Libé-Philippot and Christopher Thomas.

Cardiac regeneration leads to hyperplastic Purkinje fiber network in association with ventricular conduction disorders.

Tuning of substrate stiffness enhances mesendoderm/endoderm hiPSC differentiation by modifying their epithelial properties.

During cardiac regeneration, collaterals form rapidly to perfuse the infarcted area and help repair the coronary artery.

The transcriptional regulator Tono coordinates myogenesis in Drosophila by sensing pressure build-up in muscle nuclei.

Schwann cells undergo adaptive reprogramming to promote successful neuronal remodeling in pancreatic cancer.

Pierre-François Lenne focuses on gastrulation, an essential stage in the creation of the first tissues.

A new tool for ImageJ/Fiji to analyze automatically patterns found muscles, neurons and more.

Alterations in gut microbiota composition promotes chronic somatic pain in Myosin1a-deficient male mice.

Free diffusion of Wnt ligands can polarize target cells at distance in C. elegans embryos.

Translation starts with a Methionine: True, but not always, as revealed in a study of the PCP component Vangl2.

The brain: a permanent work in progress

Lenne and Le Bivic teams show that intestinal adherens junctions are very different from the textbook picture.

How the larval microbiota modulates the sensory modalities of future adults?

Understanding how adhesion and contractility drive a wave of tissue invagination from a subcellular perspective.

Sanjay Karki from Thomas Lecuit’s team reports that serotonin signaling regulates actomyosin contractility during embryonic axis morphogenesis in insect and bird.

Watch how model organisms are used at the IBDM to investigate normal and derailed stem cell trajectories.

Sweet Temptations: How Drosophila Suzukii’s Love for Sugar is Causing Havoc in the Agriculture Industry.

The IBDM spin-off rewarded for its innovation in a non-opioid biologic drug for pain relief.
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We are delighted to welcome Leo Guignard and his new research group ‘Computer Science, Morphogenesis and Variability’ to IBDM.

Celebrating the accomplishments of IBDM members.

Seeking for your Master internship? The IBDM seems like the right place to do it? Check out our offers.

Delta Festival 2023: Music, themed villages, and a touch of IBDM to shine under the Marseille sun.

Congratulations to Robert Kelly, Frank Schnorrer, Cédric Maurange, Bianca Habermann and Delphine Delacour!

From AFM-Téléthon Postdoc Fellow to CNRS Researcher: Qiyan Mao is advancing human muscle research through molecular and tissue mechanics approaches.

3 motivated and talented students successfully defended their thesis between February and July 2023.

We are delighted to welcome Delphine Delacour and her new research group ‘Epithelial monolayer morphogenesis’ to IBDM.

IBDM Marseille inspires young minds: engaging primary school children on childhood cancer (“Contre le cancer, j’apporte ma pierre”) and interacting with high school students through immersive experiences (DECLICS).

5 motivated and talented students successfully defended their thesis between September 2022 and January 2023.

Mike Altounian presented his work on the effects of alcohol on neural circuit development at Neurostories 2022.

EMBO elects 67 new members and associate members. They join the community of more than 1,900 leading life scientists in Europe and beyond.

The Lenne team published in Elife: using gastruloids –3D aggregates of mouse embryonic stem cells- they study at cellular resolution the specification of the endoderm.

In this study, the Mann team showed that pancreatic cancer development promotes the sprouting and growth of sympathetic axons.

The Helmbacher team identified the Fat1 Cadherin as a novel regulator of retinal vascular integrity, and investigated the underlying mechanisms.

Data published in Hum Mol Genet. confirm that Tshz3 heterozygous mice constitute a model that replicates many of the clinical problems reported in patients with TSHZ3 heterozygous conditions.

Our findings provide mechanistic insight into the mechanism by which TAFA4 reverses injury-induced mechanical hypersensitivity, by restoring normal spinal neuron activity, and highlight the considerable potential of TAFA4 as a treatment for injury-induced mechanical pain.

Through an international collaboration, using breast cancer as a biological paradigm, Flavio Maina Team publishes a work in the Theranostics journal exemplifying how specificity in targeting cell cycle regulators is essential for combinatorial cancer therapies.

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Jules Lavalou and Qiyan Mao from Thomas Lecuit’s team report that Toll-8 controls myosin-II planar polarity in Drosophila embryos and wing discs via a physical interaction with the GPCR Cirl/latrophilin.

We introduce a novel, user-friendly web-based tool ‘AnnoMiner’ to annotate and integrate epigenetic and transcription factor binding data.

The Habermann team has repurposed the concept of multilayer networks generally used to integrate different types of data.

Antoine Barrière and Amel Toudji-Zouaz in the Bertrand team developed a new method to image and quantify transcription in vivo.

This study published in Cell Death & Disease, conducted by the team of L. Kerkerian-Le Goff provides the first evidence for a role of the stress-induced protein TP53INP1 in the maintenance of neuronal homeostasis in ageing and Parkinson’s disease-related stress conditions.

Tafalgie Therapeutics is a new start-up company created in November 2020, based on the work of Aziz Moqrich’s team “Chronic pain: cellular and molecular mechanisms” at IBDM.

By combining genetics in the fruit fly Drosophila with state-of-the-art imaging and deep-learning, researchers at IBDM have found that mitochondria coordinate their formation with myofibril development to match the correct muscle type.