The actin cytoskeleton is a complex network of filaments distributed throughout the cell cytoplasm. This cytoskeleton mediates essential cellular functions such as cell migration, endocytosis,
Brain development is a complex process involving several coordinated mechanisms to fine-tune gene expression across thousands of neurons. In the Drosophila central nervous system, maturation
Muscles are crucial effectors of animal behaviour, as they translate neuronal signals into movement. Generally, most of the muscles are composed of structural and functional
Tumor innervation is increasingly recognized as a driver of cancer progression. Yet, the mechanisms that drive neural growth into tumors remain poorly understood. The aim
The morphology of dendrites shapes synaptic connectivity and therefore neuronal function. To better understand the principles governing the formation of dendritic arbors, we study two
Skeletal muscles, responsible for animal movement, are packed with the repeating functional unit characteristic of striated muscles: the sarcomere. Sarcomeres are super-assemblies of long and
Ciliary locomotion relies on local cellular components to generate coordinated movement, a strategy conserved from unicellular eukaryotes to metazoans. In most animals, the coordination and direction
Mechanical forces play a fundamental role in protein function, influencing how proteins fold, unfold (or stretch), and interact in biological systems. Specific sequence motifs and
Glioblastoma (GBM) is the most aggressive primary brain tumor in adults, marked by rapid proliferation, diffuse infiltration, and therapeutic resistance. Increasing evidence suggests that neural