During the Master’s project (M1 or M2), the student will use some of the techniques used in the laboratory to quantitatively interrogate the structure-function relationship underlying interallelic interactions.
The M1 student will learn micromanipulation, live confocal imaging, immunofluorescence and quantitative modelling techniques.
During this master project (M2) the student will apply the above method to obtain proof of principle that targeting selected candidate genes can efficiently induce or suppress intramuscular adipose tissue formation.
During this M2 project, the student will work on a recently developed model of medulloblastoma in the chick embryo.
During this master project (M1 or M2), the student will analyze the dynamics of PRC1 dots during neuronal specification and maintenance by in vivo time-lapse imaging, and characterize the nature of these dots.
The M2 project will use state-of-the-art genomics profiling techniques, Drosophila genetics, imaging and molecular biology for studying the antagonistic transcriptional control and dysfunction of fat body lipid metabolism development.
The successful completion of the project will allow you to answer how mechanical tension is generated inside human myofibers by integrating intracellular molecular forces and extracellular mechanical environment.
The M2 project will use state-of-the-art genomics profiling techniques, Drosophila genetics, imaging and molecular biology for studying muscle development.
Applicants should be interested in the quantitative aspects of cell biology, with a particular focus on marine organisms.
Annonce en anglais Project title: Investigating the mechanobiology of self-organisation in human iPSC-derived skeletal muscles Type of rotation: M1 (2 months) or M2 (6 months)
